TOMLINSONS NEW TITLES / NOVEMBER 2024

Extraordinarily detailed, step-by-step anatomic atlas informs learning and medical practice Thieme Atlas of Anatomy: Internal Organs, Fourth Edition, by renowned educators Michael Schuenke, Erik Schulte, and Udo Schumacher, along
with consulting editor Wayne Cass, expands on prior editions. This volume features reorganized and updated sections, including additional coverage of clinical applications, radiologic procedures, and illustrations covering organs of the thorax, abdomen and pelvis, and perineum. As with the widely acclaimed prior editions, anatomic concepts are presented in a step-by-step sequence with system-by-system and topographical views. The book lays a solid foundation of
anatomic knowledge, with an introductory overview of each of the organs, including discussion of embryologic development. Each of the two regional units starts with a short overview chapter, followed by the structure and neurovasculature of the region and its organs. Subsequent chapters covering topographic regional anatomy support classroom learning and active dissection in the laboratory. The new edition further delineates anatomic relationships of
inner organs, and the innervation and lymphatic systems of these organs. Key Highlights A total of 1,437 images,including new, exquisitely realistic illustrations by Markus Voll and Karl Wesker that reflect gender and ethnicity diversity
A new chapter delineates cross-sectional thorax anatomy, with stunning images by vertebra level Organs of the Digestive System and their Neurovasculature features new diagnostic imaging for colorectal and small intestine tumors, as well as hepatic illustrations Salient points for each organ are summarized in 22 high-yield fact sheets This atlas provides a robust resource for gross anatomy course instructors and medical and allied health students looking for a deeper dive
into organ system anatomy. It also provides an outstanding reference for physical therapists, yoga instructors, and related professionals. The THIEME Atlas of Anatomy series also includes two additional volumes, General Anatomy and
Musculoskeletal System and Head, Neck, and Neuroanatomy. All volumes of the THIEME Atlas of Anatomy series are available in softcover English/International Nomenclature and in hardcover with Latin nomenclature. This print book
includes complimentary access to a digital copy on https://medone.thieme.com. Publisher’s Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.

Richly illustrated with figures and examples and supplemented with a glossary of terms, The Evolutionary Roots of Human Brain Diseases assembles recent findings in clinical neuroscience, evolutionary biology, anthropology, and cellular biology to elucidate the origins of human brain diseases and how evolution has given rise to exclusive impacts on brain health only in humans. The book is succinct, up-to-date, and written by researchers across numerous disciplines, making it a compulsory read for clinical neurologists, psychologists, and all medical researchers interested in the brain. The book’s 22 chapters cover basic science concepts behind cerebral cellular specificities or humanspecific network developments, detailed discussions of neurological or psychiatric diseases and their clinical expression with an evolutionary focus, the newest imaging techniques to study the brain, future medication developments, as well as cultural and societal repercussions. Evolutionary concepts ranging from genetic pleiotropic antagonism to disease remnants of ancient behaviours crucial for survival are also presented. Insightful and innovative in its approach, this book offers a fascinating interdisciplinary dialogue on the potential repercussions of ongoing human brain evolution.

Neuroplasticity is the ability of neural networks in the brain to change through growth and reorganization. It is when the brain is rewired to function in some way that differs from how it previously functioned. How does aging affect neuroplasticity? As we grow older, plasticity decreases to stabilize what we have already learned. What influence does the aging process have on memory? Forgetfulness can be a normal part of aging. As people get older, changes occur in all parts of the body, including the brain. As a result, some people may notice that it takes longer to learn new things, they don’t remember information as well as they did, or they lose things like their glasses. This book on evolving neuroscience is unique in its lifespan focus on driving neuroplasticity in a positive direction to influence the Flynn effect of increasing human intelligence as the preferred way to prevent, delay onset, and/or reverse dementia. It considers potential impact from the first moments of life through end of life. It includes intergenerational activities. Its inclusion of centenarians and supercentenarians provides examples of “Super Agers” who have maintained and/or increased neurocognitive capacity, often with a health span that approximated their vigorous longevity. It discusses the use of the artificial intelligence (AI) revolution to refine, personalize, and broaden our global reach to enhance the Flynn effect as the preferred effort to improve global statistics on neurocognitive functioning at any age. Driving neuroplasticity in a positive direction at all ages is urgent. With this book’s focus on evidence-based interventions at any age which can have physical, emotional, neurobiological, neurochemical, immunological, and social health benefits, it is a unique overview and application of evolving neuroscience to address the UN/WHO Decade of Action for Healthy Ageing for All.

This is the seventh edition of a long-selling book (first edition 1991) that was translated into Italian, French, Chinese, Portuguese, Spanish, English. In the last ten years, stress echocardiography has exploded in its breadth and variety of applications. From a one-fits-all approach (wall motion by 2D-echo in the patient with known or suspected coronary artery disease), the field has progressed to an omnivorous, next-generation laboratory employing a variety of technologies (from M-Mode to 2D, from pulsed, continuous, color and tissue Doppler to lung ultrasound) on patients covering the entire spectrum of severity (from elite athletes to patients with end-stage heart failure) and ages (from children with congenital heart disease to the elderly with aortic stenosis). This new edition is enriched with over 300 figures, 150 tables and video-clips. In a societal and economic climate of increasing pressure for appropriate, justified and optimized imaging, stress echocardiography offers the great advantages of being radiation-free, relatively low cost, with minimal environmental impact, and with a staggering versatility: we can get more (information) with less (cost and risk). The volume will be a tremendous aid to current best practices for all health operators who intend to use stress echocardiography and ultrasound for diagnosis and guidance of optimal management in their patients.

Demystifying the science behind new cancer treatments A clear and accessible guide written in everyday language for nurses and other healthcare professionals A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy helps readers understand the science behind many of the newer drug treatments for cancer. Assuming only a basic familiarity with cell biology, this easy-to-digest guide describes how our increased understanding of cancer has been translated into the creation of new cancer treatments with a wide range of targets. Gifted communicator and educator Dr. Elaine Vickers helps you understand the mechanisms of a wide range of individual targeted therapies and immunotherapies – enabling you to communicate effectively with your colleagues and patients. Concise chapters explain how new cancer drugs and immunotherapies work, discuss their benefits, identify their limitations, and more. Now in its second edition, this popular handbook is fully revised to reflect the latest developments in targeted drug therapies and immunotherapies. Entirely new chapters on advancements in various immunotherapies are accompanied by more than 100 new and updated color illustrations. Provides an up-to-date overview of relevant treatment targets for all major cancer types, including hematological cancers Describes cancer biology and the relationship between cancer and the immune system Offers valuable insights into cell communication pathways as a common target Covers small molecule drugs, antibody-based treatments, and cellular therapies, including novel immunotherapies A Beginner’s Guide to Targeted Cancer Treatments and Cancer Immunotherapy is a must-have resource for trainees, practicing nurses, and other healthcare professionals involved in the care of cancer patients, as well as non-specialists who encounter cancer data or cancer terminology in their field.

Meet the challenges of mental health prescribing in the physically unwell with this essential guide Treating mental health conditions in physically unwell patients presents unique challenges for clinicians and other practitioners. The efficacy and safety of psychotropic medications is established in physically healthy patients. In physically unwell people, psychotropics can have different outcomes and give rise to serious adverse effects that can complicate or worsen physical health conditions. Many clinicians face difficult decisions about prescribing for mental health conditions in such cases, and reliable information for them is scarce. The Maudsley (R) Prescribing Guidelines for Mental Health Conditions in Physical Illness meets this urgent need with a comprehensive guide to the safe and effective pharmacological management of mental illness in physically unwell patients. Covering a wide range of physical health conditions and comorbidities, the book makes evidence-based recommendations on pharmacological interventions. It’s an essential resource for any clinical practitioner looking to balance the physical and mental wellbeing of people with concurrent physical and mental health conditions. The Maudsley (R) Prescribing Guidelines for Mental Health Conditions in Physical Illness readers will also find: Prescribing recommendations for mental health conditions including depression, anxiety, psychosis and bipolar affective disorder Detailed discussion of the consequences for mental health prescribing in physical health conditions such as cardiac disease, diabetes, chronic obstructive pulmonary disease, and many more Treatment of complex and frequently encountered clinical scenarios such as restarting psychotropics after overdose and steroid-induced psychiatric conditions The Maudsley (R) Prescribing Guidelines for Mental Health Conditions in Physical Illness is an essential reference for all prescribers, clinical pharmacists and nurses who work with patients with comorbid mental and physical illnesses.

Orthodontics at a Glance is part of the highly popular at a Glance series. It provides a concise and accessible introduction and revision aid. Following the familiar, easy-to-use at a Glance format, each topic is presented as a double-page spread with key facts accompanied by clear diagrams encapsulating essential knowledge. Structured over four sections, Orthodontics at a Glance covers: Craniofacial growth and development, Diagnosis and treatment planning, The management of malocclusion, Treatment techniques Orthodontics at a Glance is the ideal companion for all students of dentistry, junior clinicians and those working towards orthodontic specialization. In addition the text will provide valuable insight for general dental practitioners wanting to update their orthodontic knowledge, orthodontic nurses, therapists and technicians.

Embryology Explained is an essential guide for medical students and residents, enriched with original illustrations by Dr Thomas Newman that navigate the complexities of embryonic development. Structured methodically, the textbook breaks down embryogenesis with clarity and precision. Each chapter is organised into four main sections – embryology, clinical relevance, molecular details, and key points – allowing learners to efficiently review and connect the material with their specific academic and exam requirements. Tailored specifically to address the components of embryology emphasised in both undergraduate and postgraduate medical examinations, this book serves as an invaluable tool for exam preparation. It distinguishes itself from existing texts by shedding the common overly detailed approach and instead highlights the practical clinical applications of embryology, making it more pertinent and accessible for medical students and residents. It is an easy-to-read and comprehensive textbook that will explain embryology for you!

Epidemiology is fundamental to public health, providing the tools required to detect and quantify health problems and identify and evaluate solutions. Essential Epidemiology is a clear, engaging and methodological introduction to the subject. Now in its fifth edition, the text has been thoroughly updated. Its trademark clear and consistent pedagogical structure makes challenging topics accessible, while the local and international examples, including from the COVID-19 pandemic, encourage students to apply theory to real-world cases. Statistical analysis is explained simply, with more challenging concepts presented in optional advanced boxes. Each chapter includes information boxes, margin notes highlighting supplementary facts and question prompts to enhance learners’ understanding. The end-of-chapter questions and accompanying guided solutions promote the consolidation of knowledge. Written by leading Australian academics and researchers, Essential Epidemiology remains a fundamental resource and reference text for students and public health practitioners alike.

Practical Forensic Pathology and Toxicology is a companion to the authors’ original book on the subject, Forensic Toxicology: Mechanisms and Pathology. This new volume addresses issues that forensic pathologists face when confronted by the suspected or demonstrated presence of drugs or toxins in their cases. Since such considerations include the need for a basic understanding of the direct physiological effects of potentially toxic agents, the authors highlight various connections and interaction between forensic pathology and toxicology. The book is written for both the practicing pathologist, and those in training, who may already have some knowledge of forensic medicine but are on occasion faced with issues that reach beyond a basic determination of cause and manner of death. Pathologists are expected to provide informed, well-reasoned opinions explaining how a person died-which includes questions about any drugs, prescription medications, or otherwise that may have caused or contributed to death. As such, this book looks at the direct physiological effects of drugs and toxins, answering questions such as “Why does hypernatremia cause seizures?” or “Why can synthetic cannabinoids cause fatal complications, yet THC does not?” or the very timely “What is the mechanism by which an opiate overdose causes death?” Coverage primarily centers on the pathological derangements and physiological consequences of the actions of drugs and toxins, and the cellular mechanisms by which those pathological consequences arise. Organized using an organ system approach, sections are divided into major target organ systems and sections included for affected organs and tissues. While some drugs affect more than one organ system-and some patients will have multiple drugs present-the book’s categorization and organization take this approach to be readily usable for the reader. Case reports are included with additional patient data to show the effects of specific toxins and poisons both alone and in combination with natural disease. Color figures illustrate all aspects of drug or toxin impact on postmortem casework including the scene of death, the deceased persons, and the organs and tissues affected. Practical Forensic Pathology and Toxicology is an invaluable resource for practicing pathologists, toxicologists, and those training for those fields. It also serves as a useful reference for lawyers, judges, insurance companies, and other medical professionals who need to know, in light of what drugs are present in a particular case, what such compounds do, and how their presence (or absence thereof) is-or is not-related to an individual’s death.

Geriatric Surgery and Perioperative Care presents clear evidence to support regulatory and financial decisions in the light of the value-based care principles. The book outlines standards of care for elderly patients undergoing surgery as well as minimal requirements for modern management aimed at delivering cost-effective healthcare. It opens with the epidemiology and patho-physiological changes of aging and their impact on anesthesia and surgery. Subsequent chapters guide readers through the surgical process, addressing preoperative optimization, intraoperative procedures and management, and postoperative principles, including ICU care. The book concludes with ethical principles, care models, and hospital design to support a golden silver surgery using a team-based approach. This title is an important resource for healthcare professionals, practitioners, and others pursuing current strategies and methods for successful perioperative care of the elderly.

Bailey & Love’s Essential Operations in Hepatobiliary and Pancreatic Surgery provides step-by-step explanations of both the core operations and more complex procedures. Written by acknowledged experts and trainers from around the world, and with abundant diagrams and figures to explain the operative steps, this new resource will enable hepatobiliary and pancreatic surgeons to increase their skills in this demanding and technically challenging field. Over 70 easy-to-read chapters cover the entire range of HPB surgery. Essential management principles and technical points are included, preferred operative techniques are described and alternative options discussed. The practice of HPB surgery requires familiarity and expertise with a wide range of technologies, and these are described and integrated within the text. The text is enhanced by clear colour images, ensuring that best practice in HPB surgery is made clear and accessible for a global audience. As surgical trainees around the world continue to be faced with the reduction in training time, surgical skills need to be increasingly codified so that trainees can reach a high level of proficiency as quickly as possible. This manual ensures that surgeons will be able to access the core information that they need quickly and with ease, and in the process increase their clinical judgement, their experience and their technical skills.

Transfusion Medicine and Hemostasis: Clinical and Laboratory Aspects, Fourth Edition continues to be the only “pocket-size” quick reference for pathology and transfusion medicine for residents and fellows. It is helpful to all physicians and allied health professionals who order and administer blood components, cellular  therapies, specialized factors for hemostatic abnormalities, coagulation testing, and those who consult and care for these often very ill patients. This book is ideal for pathology, medicine, surgery, and anesthesia residents, transfusion, hematology, and anesthesia fellows, and certified and specialized practitioners, as well as medical technologist in transfusion, cellular therapy, hematology, and coagulation. This new edition covers the many new developments that have occurred since the previous edition to include new blood products, new indications, or clinical conditions in which blood products are used. Similarly, new hemostasis testing is introduced as well as new clinical scenarios due the COVID-19 pandemic that area relevant to hemostasis and transfusion medicine. This includes COVID coagulopathy, Vaccine Induced Thrombotic Immune Thrombocytopenia, Pediatric reference range in coagulation testing, Platelet rich plasma and MNC products – CAR-T cells.

Equips NPs and other primary care providers with the evidence-based knowledge to effectively treat behavioral and mental health issues in youths Amid increasing mental health concerns for children and adolescents, this important book delineates the guidelines to support nurse practitioners and other primary care providers in effectively integrating mental health care into routine pediatric primary care. The text addresses the different approaches to care in a primary care setting versus a psychiatric-focused environment and provides insights tailored to the unique challenges and opportunities encountered by healthcare professionals in integrated primary care and mental health settings. The book first focuses on incorporating mental health care into pediatric primary care settings by exploring various integration models and outlining steps for facilitating such a synthesis. It discusses how to create a therapeutic environment and addresses potential barriers to effective practice. The second section provides a detailed overview of how to conduct a mental health-focused history and physical exam, with special consideration given to age and developmental stage. The book then examines common mental health concerns of children and adolescents, covering both behavioral and developmental issues as well as psychiatric diagnosis. Chapters address epidemiology, etiology, clinical presentation, diagnostic criteria, assessment and treatment strategies, and necessary collaborations. Also included is guidance on patient and family education and follow-up recommendations. Purchase includes online access via most mobile devices or computers. Key Features: Delivers current evidence-based guidelines for effective management of mental health in pediatrics Addresses the unique features of treating the pediatric population, including the role of school and ancillary support systems Examines the differences between approaches to mental health care in primary care and psychiatric-focused settings Discusses the challenges and opportunities for healthcare professionals in integrated primary care and mental health settings Presents information in clear, easy-to-access outline format.

The Immune System: Mental Health and Neurological Conditions fully investigates how immune-related cellular, molecular, and anatomical changes impact mental functioning. The book combines human and animal studies to reveal immunological changes related to mental-health problems. In addition, users will find comprehensive information on new research related to the microbial composition of the gut microbiome and how it influences brain function and mental health. Common comorbidities with mental illness and their inherent immunological or inflammatory components are also covered. New chapters and sections on peripheral and central mechanisms in relation to viral pathogens, RNA editing to treat diseases, and COVID-19 will be included. Written by leaders in the field, the book synthesizes basic and clinical research to provide a thorough understanding on the role of immunity in neuropsychiatry. This book covers both mental-health conditions and degenerative disorders of the brain, including depression, schizophrenia, autism-like spectrum disorders, Parkinson’s disease and Alzheimer’s-like dementia.

Examines new information on critical life-sustaining technologies In its fourth edition, this highly respected resource for the cardiac surgery nurse provides the latest research findings and practical insights into providing exemplary cardiac nursing care, reflecting significant advances made in the cardiac field. This edition features an expanded chapter on Extracorporeal Membrane Oxygenation (ECMO) and a new chapter highlighting the complex protocols around Enhanced Recovery After Surgery (ERAS). Additionally, this new edition examines several new surgical techniques and their implications for nursing care. Featuring vital information for both new and seasoned nurses, this resource emphasizes evidence-based practices to ensure its information is current and clinically relevant. Purchase includes online access via most mobile devices or computers. New to the Fourth Edition: Delivers new information on ECMO and other life-saving mechanical support devices, as well as new details on ERAS in cardiac patient care Examines several new surgical techniques and their nursing implications Provides increased focus on patient-centered care Key Features: Serves as a handy pocket reference for new and experienced cardiac care nurses Provides information in quick-access format Organized for easy access to pathophysiology, equipment, procedures, and preand
post-op specialty care.

Genetic Disease Discovery and Therapeutics presents information on the methods used to determine how specific gene defects influence pathology and phenotype and to review novel therapeutic approaches designed for the treatment of specific genetic and genomic disorders. This book investigates methodologies applied to the characterization of downstream functional effects of specific gene mutations associated with altered phenotypes and clinical disease. It documents evidence of how specific mutations influence pathology and lead to disease manifestations. This book also reviews information on therapeutic approaches that could potentially be applied in diseases due to gene defects. Genetic Disease Discovery and Therapeutics is a valuable reference for scientists and graduate students involved in laboratory research related to genetics, physiology, pathology, and pharmacology as well as clinicians who encounter patients with genetic disorders.

This Open Access book is the first to provide clinicians with practical guidelines to explain the most frequently occurring neonatal brain injuries to parents and caretakers. The brains of high-risk neonates are vulnerable to injury, and brain injuries are among the most serious complications in babies admitted to neonatal intensive care units. In addition to basic explanations about the origin, extent, severity, consequences, and treatment options of different types of brain injury, the book provides illustrations and representative brain imaging examples that enable clinicians to provide parents with necessary information, presented in a clear and concise way, using lay language and explanatory drawings. There is also a section in each chapter for parents to have for themselves. Therefore, this book is a valuable resource for practitioners from various disciplines, including neonatologists, pediatricians, neurologists, (neuroand pediatric-) radiologists, neonatal nurse specialists, and physician assistants.

OSCEs Made Easy is tailored for undergraduate medical students and postgraduate medical trainees. It is a practical guide on how to prepare rigorously and systematically for OSCEs, and to secure yourself a high-scoring result. A compilation of personal revision notes combined with stories about what works well, the objective of this book is to provide every final-year medical student with the information we wish we had known going into OSCE revision. For what it is worth, all of us contributing to this book passed the OSCEs with distinctions!This book is not just an exam crammer. It is also an excellent resource for the first years on the clinical wards challenged by a complex patient on the cardiology ward, or for those who forgot how to properly examine a patient with a neurological complaint in the emergency room. The reader of this book will be provided with the resources to take a focused history, perform a proper examination, and prescribe and do basic procedures.

This comprehensive bundle comprises two vital volumes, each tailored to address key aspects crucial for providing optimal care throughout the maternal journey. Bundle includes: 9781119864714 Fundamentals of Maternal Anatomy and Physiology Addresses the unique needs of midwives by offering a dedicated exploration of anatomy and physiology with full-colour illustrations. Suitable for both undergraduate and postgraduate midwifery students, as well as practicing midwives, this book serves as an invaluable asset in advancing anatomical and physiological knowledge. Fundamentals of Maternal Pathophysiology Equips midwives with a tailored understanding of disordered physical processes, meeting the professional standards of proficiency. This foundational text emphasises the importance of early indicators, enabling midwives to recognise and promptly respond to complications during pregnancy, childbirth, and postpartum recovery. Whether you are an undergraduate or graduate midwifery student or a midwife returning to practice, this resource advances pathophysiological knowledge within midwifery practice, ensuring safe and effective care delivery.

The fourth edition of Health Promotion in Midwifery explores the principles of health promotion within the practical context of midwifery. It clearly outlines and discusses the midwife’s role in health promotion, linking theory, and practice. This thoroughly updated new edition considers recent changes and developments in midwifery practice and public health. It explores essential topics such as infant feeding, smoking, mental health, behaviour change, models for health promotion, violence and abuse, and sexual health promotion and includes seven entirely new chapters. These new additions reflect the need to improve inequalities in care for service users from a range of backgrounds such as for clients from racially diverse communities, clients from the LGBT+ communities, and migrant and displaced clients. Further chapters, such as those looking at public health in a global world, vaccinations in pregnancy, and self-care for midwives, meet needs highlighted by the recent pandemic and its aftermath. Text boxes throughout ensure the text is accessible and user-friendly, and case studies and summaries put the material in a practical context. Further reading sections encourage readers to further research and reflection on their own practice. This textbook is essential reading for all midwives, student midwives, health visitors, and other health care professionals in maternity care education and practice.

50 Studies Every Neonatologist Should Know presents a selection of seminal trials in neonatology, including both cornerstones of practice and frontiers in trial design. The included trials cover a broad range of care topics in neonatology, as well as important learning points in a number of dimensions. The text explores each trial in a dedicated chapter, with a concise summary of methods and results, accompanied by a brief discussion of special considerations, including risks of bias, interpretation, and implications for practice. Additionally, there is a short interview with the trialist (or an editorial commentary) at the end of each chapter, to give a flavor of the ongoing conversation after trial publication. As with all books in the “50 Studies” series, each study was selected using an objective selection criterion that included citations per year, high levels of evidence, clinical studies and trials, and a 3-stage Delphi review by international experts in the field. It is a must-read for neonatologists, trainees, or anyone involved in neonatal care or trial design.

The World Stroke Organization reports that “stroke has already reached epidemic proportions. Globally1 in 4 adults over the age of 25 will have a stroke in their lifetime. 12.2 million people worldwide will have their first stroke this year, and 6.5 million will die as a result.” Ischemic strokes are the most common type of stroke, with about 87% of all strokes being ischemic strokes. This new volume addresses this epidemic by presenting detailed studies on ischemic injury, with emphasis on the molecular-level mechanisms and the role of signaling pathways in the body, their structure, and their mechanism of action. The book focuses on molecular pharmacology plans and explains the new areas of research on the discovery of therapeutic molecules that can be used for combating this life-threatening disease. The authors discuss stroke occurrence at different stages of life as well as sex-based differences in its treatment. They cover aspects of the clinical treatment and diagnosis of patients with cardiovascular events, including in-depth information on the prevention, evaluation, therapy selection, result projection, and long-term course of the disease in affected patients. They also detail the involvement of platelets, neurotransmitters, renin-angiotensin-aldosterone system, and vitamin D in ischemic injury.

Handbook of Neurodegenerative Disorders: Mechanism, Diagnostic and Therapeutic Advances provides a comprehensive review on the current biomedical studies aimed at identifying the underlying causes of neurodegeneration. This book reviews the most recent developments in molecular and cellular processes altered during neurodegeneration. Divided into four parts, the first covers the mechanism of cell death in neurodegeneration. The second section reviews the recent progress in gene and gene products in neurodegeneration, including Huntington’s disease, Parkinson’s disease, Friedreich’ s ataxia, and spinal muscular atrophy. The final sections cover the current and future diagnostic techniques of neurodegenerative disorders along with therapeutic approaches.

Translational Models of Parkinson’s Disease and Related Movement Disorders focuses on cutting-edge techniques for creating and validating current Parkinson’s Disease translational experimental models. Various characteristics of these models are examined, including the prion-like properties of -synuclein, mitochondrial functions connected to the PINK1-Parkin pathway/CHCHD2, the endolysosome pathway connected to LRRK2, VPS35, and ATP13A2 using cultured cells (including patient iPS cells). This book also highlights the future possibilities of introducing new models for Parkinson’s Disease and related movements disorders, underscoring current advancements, pre-clinical and clinical developments, and future scope related to numerous models.

The go-to handbook on the current evaluation and surgical management of spinal disorders Handbook of Spine Surgery, Third Edition edited by renowned spine surgeons Ali A. Baaj, Praveen V. Mummaneni, Juan S. Uribe, Alexander R. Vaccaro, and Mark S. Greenberg reflects new techniques introduced into the practice since publication of the last edition, along with four-color images and videos. The book is organized into four parts and 66 chapters, starting with basic spinal anatomy. Part II covers the physical exam, electrodiagnostic testing, imaging, safety issues, intraoperative monitoring, bedside procedures, and the use of orthotics, pharmacology, and biologics. Part III discusses a full range of spinal pathologies and the final section concludes with 34 succinct procedural chapters. Key Highlights Contributions from an expanded “who’s who” of spine surgery experts New chapters cover state-of-the-art techniques, including endoscopy, CT-guided navigation, robotics, augmented reality, and vertebral body tethering Procedural chapters include key points, indications, diagnosis, preoperative management, anatomic considerations, techniques, surgical pearls, and more This is an invaluable resource for neurosurgical and orthopaedic residents, spinal surgical fellows, and practicing orthopaedic surgeons and neurosurgeons who specialize in spine surgery. This print book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher’s Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.

Cardiac MRI: Clinical Uncertainty and Patient Outcomes weaves together the essentials of clinical cardiology with advanced principles of cardiac magnetic resonance imaging. This case-based atlas reviews a variety of cases where clinical management was modified after CMR revealed an alternative diagnosis than initially suggested by clinical data. It includes over 40 clinical scenarios covering a wide spectrum of common and uncommon cardiac conditions, and how CMR can be utilized in differentiating these disease processes which often have no other method of being diagnosed. This book defines how Cardiac MRI can serve as a valuable tool in the diagnosis of complex cardiac pathologies and aid in the complex treatment management of these patients, whilst key points regarding the limitations of cardiac tests (e.g. EKG, echocardiography, stress tests, catheterization etc.) are highlighted. Additional imaging pearls regarding CMR modalities and image acquisition are also included with each case.Through this book, clinicians in both subspecialty and primary can understand when to order a cardiac MRI for their patient and the clinical questions it can help the provider solve. The book serves as a reference tool for both cardiologists and radiologists in terms of elucidating how CMR can be utilized as a clinical diagnostic tool to guide management. Whether you take care of complex patients or interpret advanced imaging modalities, like echocardiography or Cardiac MRI, this book is for you!

Effectively perform and interpret MR body imaging with this concise, highly illustrated resource! Fundamentals of Body MRI, 3rd Edition, covers the essential concepts residents, fellows, and practitioners need to know, laying a solid foundation for understanding the basics and making accurate diagnoses. This easy-to-use title in the Fundamentals of Radiology series covers all common body MR imaging indications and conditions, while providing new content on body MRI emergencies, physics, and noninterpretive skills with an emphasis on quality and safety. Covers all common body MR imaging content, along with discussion of how physics, techniques, hardware, and artifacts affect results-all summarized in an easy-to-read format with practical applications throughout. Features more than 1,600 detailed MRI images and 100 algorithms and diagrams that highlight key findings and help you grasp visual nuances of images you’re likely to encounter. Contains extensively revised content on liver lesions, including new coverage on LI-RADS system, and new safety tips and guidelines that keep you up to date. Includes new information on MR defecography and advances in rectal cancer staging and post-treatment imaging, including new content on inflammatory bowel disease. An eBook version is included with purchase. The eBook allows you to access all of the text, figures and references, with the ability to search, customize your content, make notes and highlights, and have content read aloud. Any additional digital ancillary content may publish up to 6 weeks following the publication date.

McDonald’s The Nurse Educator’s Guide to Assessing Learning Outcomes, Fifth Edition is a comprehensive guide for nurse educators that covers the assessment of critical thinking, the development of learning objectives, and the creation of tests, including detailed tips for writing many kinds of individual test items. This unique resource also covers the analysis of test reliability. Examples of effective and ineffective test items are included throughout to help faculty and nurse educators deepen their understanding of how to create effective tests and assess student learning. The updated Fifth Edition features two new chapters dedicated to the NextGen NCLEX to prepare faculty to develop questions for their students, addressing the move from critical thinking to clinical judgment.

Generate and apply high-quality research in a nursing context with this accessible guide The production and application of rigorous, effective research can have a significant impact on nursing care. Notes On… Nursing Research offers an overview of nursing research, its relationship with clinical practice and patient outcomes, and its positive effects on the nursing professional. Beginning with an introduction to the fundamental principles of nursing research, it moves through the stages of designing and conducting research studies before concluding with specific applications of research to clinical practice and patient care. Notes On… Nursing Research readers will also find: A step-by-step guide to formulating and answering a research question Detailed discussion of research methodologies including data collection and analysis, inferential statistics, multivariate statistics, evidence synthesis, and much more Specific examples showing how research has improved patient care and outcomes Notes On… Nursing Research is ideal for undergraduate nurses, as well as a valuable resource for qualified and practicing nurses and other health professionals looking to develop their understanding of research.

Colorectal Cancer Treatment Resistance: Mechanisms, Insights, Advances and Solutions provide insights, knowledge, and potential solutions for healthcare professionals, researchers, and individuals affected by colorectal cancer. The book discusses innovative therapies, personalized medicine, and the latest scientific advancements in the field, all aimed at enhancing the effectiveness of treatment and improving the prognosis for colorectal cancer patients. It elucidates on the broader context of cancer research and treatment strategies that have the potential to impact the overall approach to managing colorectal cancer and, by extension, other types of cancer that may exhibit similar resistance challenges. By studying and addressing resistance mechanisms, researchers and healthcare professionals can work towards improving patient outcomes and the overall quality of cancer care.

This book provides an update on the current understanding of various aspects of bladder cancer biology and introduces clinical manifestations together with current and novel treatment aspects. Key concepts covered include epidemiology and genetic predisposition to bladder cancer, insights into the mutational events and molecular pathogenesis of bladder cancer, detailed analyses of tumor subtypes, and references to common experimental models used in the study of bladder cancer. The book addresses critical issues such as the molecular features that contribute to the development of bladder cancer, the impact of the tumor microenvironment on disease progression, and the potential of novel urine- and blood-based biomarkers for diagnosis and treatment. Innovative therapeutic applications are also explored, including targeting immune checkpoints and personalized medicine approaches. Aimed at early career and experienced researchers or clinicians alike, this volume provides an interdisciplinary understanding of bladder cancer. Delving into the biology, pathology, and clinical aspects of the disease, it serves as an indispensable resource for understanding bladder cancer’s complexity.

Navigate Complex Cases with Confidence and Precision The field of otorhinolaryngology is made challenging by the complex and unique anatomy of head and neck region. Successfully navigating this area with surgical finesse remains an enigma. 100 Complications of Otorhinolaryngology & Skull Base Surgery provides a broad overview of various complications encountered in ENT and skull base surgeries, their impacts, and intricacies in their management. “A successful surgeon has the eyes of a hawk, heart of a lion, and hand of a lady.” True to this quote, a surgeon is not the one who is just well versed in surgical techniques, but the one who handles complications too with aplomb. This book features 100 complicated yet interesting cases by more than 250 authors from 26 different countries, discussing the start of scary times, how they managed to tackle those in an appropriate manner, and the lessons they learnt from each case. Each case report has a section on “Clinical Pearls and Pitfalls” in order to broaden the perspective. Key Features A collection of real-life cases and complications faced by senior ENT surgeons across the world. 100 unique cases, and each case is led by a different team head. Contains over 700 operative and endoscopic images, illustrations serving as a visual guide for the readers. Over 50 videos of various clinical conditions for better visual understanding. This book serves as a guide for otorhinolaryngologists in handling complicated cases. ENT surgeons will also find this book beneficial if they encounter critical complications during surgery. Smears in the Rapid Diagnosis of Central Nervous System Lesions Challenges in the Interpretation of Stereotactic Biopsies This print book includes complimentary access to a digital copy on https://medone.thieme.com. Publisher’s Note: Products purchased from Third Party sellers are not guaranteed by the publisher for quality, authenticity, or access to any online entitlements included with the product.

Bacterial Enzymes as Targets for Drug Discovery: Meeting the Challenges of Antibiotic Resistance addresses the gap between medical microbiology, structural biology, and genomic science in the development of new antibacterial drug development. This book consolidates detailed profiling of bacterial target enzyme families for the drug discovery process and methodologies for use and validation of the potential drug targets. The content covers the foundations of antibiotic drug discovery process and focuses on bacterial enzymes as drug targets, building a bridge between microbiology, structural biology, and genomic science. This is the ideal reference for antibiotic drug discovery researchers in the pharma industry and academia. Biochemists, microbiologists, and medicinal chemists will also benefit from this books’ content.

Delivers a breadth of content encompassing all aspects of psych-mental health care along the provider continuum This unique clinical reference supports APRNs and PMH-NPs as they strive to provide high-quality evidence-based care to patients with mental health issues and conditions. Designed to support the ongoing needs and changing practice requirements of these nursing professionals, this new text provides a comprehensive examination of best-practice psychiatric methods, ethical concerns, patient assessment, and management strategies. These accessible guidelines for clinicians in a variety of settings bring together scientific skills backed by theory and professional knowledge along with helpful recommendations to bolster the clinician’s psychiatric skills. With an easy-to-navigate format, the book encompasses five distinct sections covering general psychiatric nursing guidelines, diagnostic specific procedures and patient treatment planning, cultural and other considerations for special populations, the administrative basics for establishing an APRN practice, and additional topics related to mental health. Reflecting expertise from authors versed in varied practice fields and numerous subspecialties, the resource combines evidence-based practice, advanced research, and practical, humanistic approaches. Purchase includes online access via most mobile devices or computers. Key Features: Provides comprehensive psychiatric-mental health guidelines to advanced practice nurses in easy-to-access format Delivers step-by-step coverage of conducting psychiatric assessments and making referrals Covers polypharmacy, differential diagnosis, and patient education Includes coverage of special populations including LGBTQ+, homeless and indigent, veterans and survivors of war, and many others.

Healthcare is inextricably bound to productivity, efficiency, and economic development. Although many methods for analyzing productivity and efficiency have been extensively covered, relatively little focus has been placed on how those methods can be applied to health care in a coherent and comprehensive manner. The Cambridge Handbook of Healthcare outlines current foundations and states of the art on which future research can build. It brings together experts in this growing field to cover three key sources and aspects of human welfare – productivity, efficiency, and healthcare. Beginning with academic focused chapters, this book bridges and provides outreach to the practice and regulation of the health care industry and includes academic and regulatory perspectives, including overviews of major evidence from international empirical applications. Each chapter is dedicated to a particular topic and delivered by international experts on that topic.

This easy-to-understand pocketbook in the highly respected Clark’s series of diagnostic imaging texts introduces students and practitioners to the concepts of management, leadership and business planning, and outlines the knowledge and skills required to maintain the daily functioning of a medical imaging and radiotherapy department. Recognising that the transition from clinical radiographer to team lead or manager can be challenging, the book provides a good knowledge of management functions that will assist in this development and enable further progression into operational management roles. Clark’s Essential Guide to Operational Management and Business Practice in Medical Imaging and Radiotherapy takes the systematic approach adopted within books in the Clark’s series and is designed to be clear and consistent, introducing the reader to differing concepts of management. All involved in managing imaging delivery and practice, no matter what the area of service, will benefit greatly from this publication.

Small Lungs and Obstructed Airways: Reassessing Chronic Obstructive Pulmonary Disease proposes an alternative perspective to current explanations for the distribution of chronic lung disease. The book considers the link between chronic respiratory disease and associated mortality with smaller lungs rather than obstructed airways and explores other factors contributing to poor lung health besides the current emphasis on the roles of air pollution, occupational exposures, and cardio-metabolic disease. It presents the findings of the Burden of Obstructive Lung Disease (BOLD) study, sharing new views on the prevalence of obstructive lung disease and risk factors across various global regions. Sections cover decreased lung function, including the prevalent views on the impact of both household and external air pollution, occupational exposure, and the prenatal and postnatal/childhood environment in the etiology of impaired lung function and COPD. The book then moves on to discussions on the impact poverty and nutrition has on lung health, sharing the findings of the BOLD study regarding its effect on lung function and risk of COPD in lower-income countries. The book closes with a chapter outlining the clinical and public health implications of the findings discussed in the book.

In the hands of a skilled operator, ultrasound scanning is a simple and easy procedure. However, reaching that level of proficiency can be a long and tedious process. Commended by the British Medical Association, Practical Ultrasound, Third Edition incorporates up-to-date techniques and protocols, focusing on the scans regularly encountered in a busy ultrasound department. This book provides everything novice practitioners need to know to become competent and skilled in scanning. Beginning with the general principles of ultrasound scanning and a guide to using the ultrasound machine, this book provides clear instructions on how to perform scans supplemented by high-quality images and handy tips. Organized according to anatomical site, the chapters include a review section on useful anatomy, scan protocol presented step by step, and a section on common pathology. Maintaining the popular format of the first and second editions, each chapter contains examples of common and clinically relevant pathologies and notes on the salient features of these conditions. The authors’ precise approach puts an immense amount of knowledge within easy reach, making it an ideal aid for learning the practicalities of ultrasound. Key Features: Follows an appealing organization of chapters, developing fundamental knowledge of how to operate the ultrasound machine before moving on to the practicalities of how to scan each anatomical area Presents comprehensive, authoritative, and up-to-date text, integrating anatomical knowledge, practical tips from experts, and common clinical pathologies that are important to recognize Incorporates high-quality ultrasound images with corresponding line drawings indicating the key points to spot Arms you with the practical knowledge you will need when you pick up the ultrasound probe and start out on your own journey of learning the skill of ultrasonography.

Providing real-world case examples and realistic mock examples of vascular surgery emergencies and clinical scenarios, this illustrated text supports trainees and residents in their daily clinical practice. However, the focus on senior decision-making and complex clinical management scenarios will also help trainees prepare for the FRCS (Vasc) and other specialist Vascular Surgery exams. Indeed, making efficient and appropriate clinical decisions is one of the most important and challenging parts of postgraduate vascular surgical training. These realistic cases will teach trainee vascular surgeons to develop their diagnostic and management skills, expand their experience, and ultimately should empower them to form more advanced clinical management plans that reflect higher level thinking. Key Features Teaches the surgical trainee how to navigate real-world clinical scenarios Reinforces the practical application of basic principles Encompasses challenging cases Provides question and answer options Case reflections indicate the rationale behind the decision-making A broad range of clinical conditions are covered to ensure that the trainee vascular surgeon can respond with confidence when presented with difficult new case scenarios.